In vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni was .. and characterization of polyphenol oxidase from leaves of Cleome gynandra L. Food . Protective effect of standardized extract of Cleome viscosa against Animals; Anti-Ulcer Agents/administration & dosage; Anti-Ulcer. Research Journal of Pharmacognosy and Phytochemistry. Delivering full text access to the world’s highest quality literature.

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The NO radicals scavenging activity was calculated. The slides were examined microscopically for pathomorphological changes such as congestion, hemorrhage, edema, and erosions using an arbitrary scale for the assessment of severity of these changes. Ethanol extract prepared from the leaves of B. The collected fresh matured leaves of B. Nowadays, most of the people include natural antioxidants as nutraceuticals or as food additives.

Evaluation of Antiulcer and Antioxidant Activity of Barleria gibsoni Dalz. Leaves

Given the many side effects of modern medicine, the initial acquisition of fewer side effects, and medication of indigenous drugs, it should be considered as a better alternative for the treatment of peptic ulcer. Antiulcer activity of ethanol extract obtained from Barleria gibsoni leaves: Ligation was done without causing any damage to the blood supply of the stomach.

Pyloric ligation-induced gastric ulcer In pyloric ligation-induced ulcer model, oral administration of leaves in two different doses showed significant reduction in ulcer index, gastric volume, free acidity, and total acidity as compared to the control group, whereas omeprazole as reference standard drug showed a significant reduction in ulcer index, gastric volume, free acidity, and total acidity [ Table 2 ].

Tambolihas pursuing Ph.

Nitric oxide radical scavenging activity NO radical scavenging activity of EBG was performed by the formation of NO using sodium nitroprusside. AcanthaceaeBarleria gibsonigallic acid, L-ascorbic acid, pylorus ligation-induced ulcer model, quercetin. On pylorus ligation-accumulated secretions and the related ulcers confirm gastric acid output to be the basic cause of gastric ulcers.


By conversion of the unpaired cleme to paired electron by hydrazine due to the hydrogen donating ability of the extract. DNA damage protecting activity and antioxidant potential of pudina extract.

RJPT – Antiulcer and Analgesic Activity of the Ethanol Extract of Cleome gynandra Linn Leaves.

Kumar A, Chattopadhyay S. The seeds and its oil have antihelminthic properties but they are ineffective in treating roundworm infections.

NO radical scavenging of EBG was carried out as previously described. The ethanol EBG leaves demonstrated decreasing oxidative stress and increasing percentage preventive index compared to ascorbic acid and omeprazole, respectively.

Some of the important species of this genus are Barleria prionitis, Barleria greenii, Barleria albostellata, Barleria cristata, Barleria strigosa, Barleria Tomentosaetc.

Nitric oxide radical scavenging activity NO radical scavenging of EBG was carried out as previously described. Table 2 Effect of B. However, more work is required for the isolation and characterization of the active principles responsible for these activities.

Antiulcer Herbs

A significant decrease was observed in the DPPH radical activity due to the scavenging ability of the extracts. Flavonoid content and antioxidant activities from Cinnamomum species. Gayathri R, Anuradha V. The results of the histopathological investigation of B.

Capparidaceae is also known as Tickweed, or Spider plant. He is life member of APTI. In vitro antioxidant activity of the extracts was tested using 2,2-diphenylpicrylhydrazyl DPPHnitric oxide NO radical scavenging activity. From the present study results reveals the antiulcer activity of ethanol extract leaves which is comparable to that of Omeprazole.

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The whole herb is used in treatment of inflammation of the middle ear and applied on wounds and ulcers, so the research was to prove experimentally anti ulcer activity in whole plant of Cleome viscosa linn. Nitric Oxide, IC In Asia and Africa antuilcer leaves and seeds used as a rubefacient and vesicant and to treat infections, fever, rheumatism and headache.

Thus, the antiulceer of the present investigation was to evaluate in vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni leaves extract EBG. Protective effect of Rhinax, a herbal formation against physical and chemical factors induced gastric and duodenal ulcers in rats.

Capparidaceae is also known as Tickweed, or Spider plant. J Pharm Sci Res. Anti-inflammatory, anticholinesterase, antioxidant and phytochemical properties of medicinal plants used for pain-related ailments in South Africa.

In vitro antioxidant activity of Barleria noctiflora L. Evaluation of antioxidant potential of selected mangrove plants. The animals were housed in colony cages and maintained under standard environmental conditions: From the present study, ethanol EBG results reveal that antioxidant and antiulcer activity is equipoint to that of omeprazole. The ethanol extract of leaves demonstrated increase in percentage preventive index compared to omeprazole respectively.

From the incubated mixture, 0. The effect of alcoholic extract of Cleome viscosa linn. The ethanolic EBG leaves revealed the presence of alkaloids, saponins, terpenoids, flavonoids, steroids, cardiac glycosides, tannins, aminoacids, and proteins [ Table 1 ]. All the chemicals used in this study including the solvents were of analytical grade.